Postdoctoral fellow
I am interested in the mechanisms and potential therapeutic strategies for neurodegenerative diseases. Using Drosophila as my primary model system, I investigate the roles of disease-associated genes in the onset and progression of neurodegeneration. I am also interested in rare diseases, aiming to better understand neurodegenerative processes by exploring the association between identified clinical phenotypes and their underlying genetic variations.
Zhao Y*, Xiong C*, Wang B, Li D, Liu J, Wei S, Hou Y, Zhou Y#, Zheng R# (2025). The Discovery of Phages in the Substantia Nigra and Its Implication for Parkinson's Disease Research 8 0657 Abstract
Wang B, Hu Z, Cui L, Zhao M, Su Z, Jiang Y, Liu J, Zhao Y, Hou Y, Yang X, Zhang C, Guo B, Li D, Zhao L, Zheng S, Zhao Y, Yang W, Wang D, Yu S, Zhu S, Yan Y, Yuan G, Li K, Zhang W, Qin L, Zhang W, Sun F, Luo J, Zheng R (2024). BetaAR-mTOR-lipin1 pathway mediates PKA-RIIBeta deficiency-induced adipose browning Theranostics 14(13) 5316-5335 Abstract
Zhao Y, Wang B, Zhao M, Liu J, Hou Y, Wei S, Xiong C, Li D, Zheng R (2024). Age-related decline of PKA-RIIBeta level in SNc dopaminergic neurons underlies PD pathogenesis bioRxiv DOI 10.1101/2024.09.13.612981
Liu J, Wang B, Su Z, Han X, He M, Zhao Y, Hou Y, Li D, Zhang W, Qin L, Wang K, Li Y, Yan Y, Yu S, Huang X, Yuwen T, Zheng R (2024). Identification of leptolin as a novel anti-obesity adipokine bioRxiv DOI 10.1101/2024.09.03.610963
Wang B, Zhao M, Su Z, Jin B, Yang X, Zhang C, Guo B, Li J, Hong W, Liu J, Zhao Y, Hou Y, Lai F, Zhang W, Qin L, Zhang W, Luo J, Zheng R (2023). RIIBeta-PKA in GABAergic Neurons of Dorsal Median Hypothalamus Governs White Adipose Browning Advanced Science 10(5) e2205173 Abstract
Zhao M, Wang B, Zhang C, Su Z, Guo B, Zhao Y, Zheng R (2021). The DJ1-Nrf2-STING axis mediates the neuroprotective effects of Withaferin A in Parkinson's disease Cell Death & Differentiation 28(8) 2517-2535 Abstract
Ren X, Zhao Y, Xue F, Zheng Y, Huang H, Wang W, Chang Y, Yang H, Zhang J (2019). Exosomal DNA Aptamer Targeting alpha-Synuclein Aggregates Reduced Neuropathological Deficits in a Mouse Parkinson's Disease Model Molecular Therapy Nucleic Acids 17 726-740 Abstract